Krishna Kumar
Robinson Professor of Chemistry Tufts University
Seminars
Wednesday 15th April 2026
Advancing a Unimolecular Tetra-Agonist to Treat Obesity, Diabetes, Cancer & Cardiovascular Disease for a Single-Drug Solution for a Range of Complex Conditions
8:30 am
- Activating four distinct hormone receptors at once to provide more consistent and durable weight loss, potentially rivalling bariatric surgery, for a non-invasive alternative to a significant and lasting solution to obesity
- Balancing hormonal actions with a tetra-agonist design to mitigate the common side effects of current drugs, such as nausea and muscle loss, for improved patient tolerability and long-term adherence to therapy
- Creating a single, unimolecular compound to simplify the treatment regimen, avoiding the need for multiple drugs, for a more convenient and accessible therapeutic option for patients with complex comorbidities
