Beyond Incretins: Exploring the Quality of Weight Loss with AZD6234, a Novel Selective Amylin Receptor Agonist, and GLP-1RA Combinations in DIO Rats
Time: 8:00 am - 9:00 am
day: Day One
Details:
- AZD6234 is a long-acting, selective amylin receptor agonist that mediates dose-dependent decreases in food intake and body weight change in obese rats
- Switching to AZD6234 after GLP1RA prevents body weight rebound and increases weight loss when combined with GLP1RA in obese rats
- AZD6234 promotes fat mass loss while preserving lean mass without compromising tolerability in pre-clinical models
